Strain Improvement

日期：2022-12-09 阅读量：904

l Rational mutation using physical and chemical mutagenesis for strain improvement

l Efficient expression, site-directed mutagenesis, directed evolution, modification and reconstruction, whole genome or chromosome transfer using genetic engineering for strain improvement

l Using synthetic biology and AI+ learning, the optimal catalytic module is screened under the guidance of engineering ideas through gene sequencing, gene synthesis, gene editing and genomics. The target gene from this optimal module is further transferred into Escherichia coli, yeast or filamentous fungus to construct the corresponding chassis and experiment the shake flask fermentation for strain improvement